Description

n-Boc-D-Alaninol is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for constructing complex molecules, where the Boc (tert-butoxycarbonyl) group offers orthogonal protection for the amine functionality. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds requiring precise stereochemistry.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for peptide drugs and enzyme inhibitors.
• Peptidomimetics: Used to construct non-natural peptide analogs with enhanced metabolic stability and bioavailability.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexation.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein function.
• Material Science: Can be incorporated into polymers and specialty materials to impart chirality and specific functional groups.

Basic Information

Product Name	n-Boc-D-Alaninol
CAS No.	106391-86-0
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)propan-1-ol; D-Alaninol, N-BOC-; (R)-N-Boc-2-amino-1-propanol; tert-Butyl (R)-(1-hydroxypropan-2-yl)carbamate; N-(tert-Butoxycarbonyl)-D-alaninol; Boc-D-Ala-ol; Boc-D-Alaninol; (R)-N-Boc-alaninol
EINECS	Contact for details

Quality Control

Our n-Boc-D-Alaninol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using a desiccant and storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.