Description

Oxytocin, Pen(1)-(4-Mephe)(2)-Thr(4)-Orn(8)- is a synthetic analogue of the neuropeptide hormone oxytocin, designed with specific amino acid substitutions to enhance its stability and receptor-binding profile. This high-purity peptide is critical for advanced biochemical research and pharmaceutical development, offering a reliable tool for studying oxytocinergic pathways and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuroendocrinology, peptide therapeutics, and drug discovery.

Application

• Biochemical Research: A key reagent for studying the structure-activity relationships (SAR) of oxytocin and vasopressin receptor families.
• Pharmaceutical Development: Serves as a reference standard or an active pharmaceutical ingredient (API) intermediate in the development of novel peptide-based therapeutics targeting neurological and reproductive disorders.
• Neuroscience Studies: Used in in vitro and in vivo models to investigate the role of oxytocin in social behavior, stress response, and memory.
• Receptor Binding Assays: Employed in competitive binding studies to characterize receptor affinity and selectivity for drug candidate screening.
• Peptide Chemistry: Acts as a model compound for developing new synthetic methodologies, purification techniques, and stability studies for complex peptides.

Basic Information

Item	Details
Product Name	Oxytocin, Pen(1)-(4-Mephe)(2)-Thr(4)-Orn(8)-
CAS No.	106128-84-1
Molecular Formula	C46H68N12O12S2
Molecular Weight	1021.23 g/mol
Synonyms	[Pen1,4-MePhe2,Thr4,Orn8]-Oxytocin; 1-(3-Mercaptopropanoic acid)-2-(4-methyl-L-phenylalanine)-4-L-threonine-8-L-ornithine-oxytocin; Oxytocin (1-6)-hexapeptide, 7-(L-2-aminobutyric acid)-8-L-ornithine-9-glycinamide; Oxytocin analogue; [Penicillamine1, 4-methylphenylalanine2, threonine4, ornithine8]oxytocin; Atosiban Impurity; Tocolytic peptide analogue
EINECS	Contact for details

Quality Control

Our Oxytocin, Pen(1)-(4-Mephe)(2)-Thr(4)-Orn(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against stringent in-house specifications to ensure consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (Karl Fischer)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.