Description

Fibroblast Growth Factor, Basic, Human is a high-purity, recombinant protein crucial for cellular signaling and development. This growth factor plays a vital role in promoting the proliferation, differentiation, and survival of a wide range of cell types, particularly those of mesodermal and neuroectodermal origin. It is an essential reagent for researchers and manufacturers in advanced cell culture, tissue engineering, and biopharmaceutical development, enabling groundbreaking work in regenerative medicine and therapeutic discovery.

Application

• Cell Culture & Tissue Engineering: A key supplement in serum-free and defined media for the expansion and maintenance of stem cells, fibroblasts, chondrocytes, and endothelial cells.
• Biopharmaceutical R&D: Used in research for wound healing, angiogenesis, neuroprotection, and as a critical component in developing cell-based therapies and organoid models.
• Regenerative Medicine Studies: Investigated for its potential to promote tissue repair and regeneration in preclinical models for neurological disorders, cardiovascular diseases, and bone healing.
• Diagnostic Development: Employed in assay development and as a standard in ELISA kits to quantify bFGF levels in biological samples for research purposes.
• Biomanufacturing Process Optimization: Used to enhance cell viability and productivity in bioreactor systems for the production of other therapeutic proteins and vaccines.

Basic Information

Item	Detail
Product Name	Fibroblast Growth Factor, Basic, Human
CAS No.	106096-93-9
Molecular Formula	C620H1005N179O191S9 (Approximate, for 146 aa form)
Molecular Weight	~16.4 kDa
Synonyms	Basic Fibroblast Growth Factor; bFGF; FGF-2; FGF-b; Heparin-binding growth factor 2; Prostatropin; Recombinant Human FGF-basic; HBGF-2; Fibroblast Growth Factor 2 (Human)
EINECS	Contact for details

Quality Control

Our Fibroblast Growth Factor, Basic, Human is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing specifications such as purity by HPLC, endotoxin levels, biological activity in cell-based assays, and sterility. Our quality commitment aligns with standards relevant for research and bioprocessing applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE & HPLC)	≥ 95%
Biological Activity	Determined by cell proliferation assay (e.g., Balb/c 3T3)
Endotoxin	< 1.0 EU/µg
Sterility	Sterile (0.22 µm filtered)
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.