Description

2-Fluoro-Cyclopropanamine is a specialized fluorinated cyclopropane derivative, a high-value building block in modern synthetic chemistry. Its unique structure, combining the strained cyclopropane ring with a fluorine atom and an amine group, makes it a critical intermediate for introducing conformational rigidity and fluorine-based bioisosterism into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to optimize the potency, metabolic stability, and physicochemical properties of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Investigated as a monomer or precursor for developing novel fluorinated polymers with specific thermal or surface properties.
• Ligand Development: Utilized in medicinal chemistry for constructing constrained peptide mimetics and novel ligands for biological targets.

Basic Information

Product Name	2-Fluoro-Cyclopropanamine
CAS No.	105919-28-6
Molecular Formula	C3H6FN
Molecular Weight	75.09 g/mol
Synonyms	2-Fluorocyclopropanamine; 2-Fluorocyclopropylamine; 1-Amino-2-fluorocyclopropane; (±)-2-Fluorocyclopropanamine; trans-2-Fluorocyclopropanamine; 2-Fluoro-1-cyclopropanamine; 2-Fluorocyclopropaneamine; (2-Fluorocyclopropyl)amine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-Cyclopropanamine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.