Description

Cyclopropanecarboxylic Acid, 2-Fluoro-2-Methoxy-, Methyl Ester, trans- (9Ci) is a high-purity fluorinated cyclopropane derivative, a crucial chiral building block in advanced organic synthesis. Its unique trans-configuration and fluorine-methoxy substitution pattern make it a valuable synthon for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Research: Used in the development of novel herbicides and insecticides, where the fluorinated cyclopropane moiety can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Investigated for incorporation into specialty polymers and liquid crystals to modify physical and optical properties.
• Chemical Biology Probe: Utilized as a building block for labeled compounds or molecular probes to study biological mechanisms.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-2-Methoxy-, Methyl Ester, trans- (9Ci)
CAS No.	105783-74-2
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	trans-Methyl 2-Fluoro-2-methoxycyclopropanecarboxylate; Methyl (1R,2S)-2-Fluoro-2-methoxycyclopropanecarboxylate; Methyl (1S,2R)-2-Fluoro-2-methoxycyclopropanecarboxylate; 2-Fluoro-2-methoxycyclopropanecarboxylic acid methyl ester, trans-; trans-2-Fluoro-2-methoxycyclopropanecarboxylic Acid Methyl Ester; (1R,2S)-rel-2-Fluoro-2-methoxycyclopropanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Fluoro-2-Methoxy-, Methyl Ester, trans- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. We provide comprehensive analytical data including chiral purity confirmation. Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be sensitive to moisture and strong bases; handle and store under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.