Description

Proteoglycan 19 CAS NO 105436-41-7 is a specific, high-purity proteoglycan compound, a complex macromolecule consisting of a core protein with covalently attached glycosaminoglycan (GAG) chains. This biomolecule is critical for advanced research and development in life sciences, particularly in studying extracellular matrix (ECM) structure, cell signaling, and tissue engineering. It is essential for pharmaceutical developers, academic researchers, and biotechnology companies focused on regenerative medicine, dermatology, and osteoarthritis research.

Application

• Biomedical Research: Used as a key reagent in studies of cartilage biology, joint health, and extracellular matrix (ECM) interactions.
• Pharmaceutical Development: Serves as a reference standard or active ingredient candidate in formulations targeting osteoarthritis, wound healing, and dermatological conditions.
• Tissue Engineering & Regenerative Medicine: Incorporated into scaffolds and biomaterials to promote cell adhesion, proliferation, and differentiation for cartilage and bone repair.
• Cosmeceutical Formulations: Utilized in high-end skincare products for its potential hydrating and skin-rejuvenating properties, mimicking natural ECM components.
• Diagnostic Assay Development: Acts as a coating antigen or standard in immunoassays and biochemical tests designed to detect ECM-related biomarkers.
• Cell Culture & Stem Cell Research: Applied as a substrate to create a more physiologically relevant environment for culturing specialized cells like chondrocytes and mesenchymal stem cells.

Basic Information

Product Name	Proteoglycan 19
CAS No.	105436-41-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PG 19; Proteoglycan-19; Aggrecan Proteoglycan Fragment; Cartilage Proteoglycan 19; ECM Proteoglycan 19; Chondroitin Sulfate Proteoglycan 19; CSPG19; PG19 (Biochemical)
EINECS	Contact for details

Quality Control

Our Proteoglycan 19 is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC, identity confirmation, and biological activity checks where applicable, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere or desiccated conditions upon opening. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR/HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content (Bradford)	Reported per COA
Glycosaminoglycan (GAG) Content	Reported per COA
Moisture Content (KF)	≤ 5.0%
Biological Activity (if applicable)	Reported per COA
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.