Description

Prothrombin Clamart is a highly purified protein complex derived from clam blood, primarily used as a critical reagent in coagulation diagnostics and research. Its precise activity and standardized nature make it essential for ensuring the accuracy and reliability of hemostasis testing systems. This product is indispensable for manufacturers of in-vitro diagnostic (IVD) kits, clinical research laboratories, and facilities conducting advanced studies in blood coagulation pathways.

Application

• As a key component in the manufacturing of calibrators and control plasmas for coagulation analyzers.
• For use in prothrombin time (PT) and activated partial thromboplastin time (aPTT) test reagents.
• As a defined substrate in research investigating vitamin K-dependent coagulation factors and related disorders.
• In the development and quality control of factor-deficient plasmas used for specific factor assays.
• For studying the effects of anticoagulant drugs, such as warfarin, on the extrinsic pathway of coagulation.
• As a critical material in the standardization and validation of new hemostasis testing methodologies.

Basic Information

Product Name	Prothrombin Clamart
CAS No.	105418-28-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Clam Prothrombin; Prothrombin (Clam); Marine Prothrombin; Coagulation Factor II (Clam); Tachypleus tridentatus Prothrombin (common mis-association); Blood Clotting Factor II; Prothrombin Complex (Clam); Clamart Factor
EINECS	Contact for details

Quality Control

Our Prothrombin Clamart is manufactured under strict quality systems to ensure batch-to-batch consistency and performance. Each lot is tested for specific activity, purity, and stability using validated methods. Certificates of Analysis (COA) detailing purity, activity units, and functional performance in standardized assays are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Functional)	Conforms (Activates standard plasma)
Specific Activity	≥ [Value] units/mg protein
Purity (SDS-PAGE)	≥ 95%
Moisture (Karl Fischer)	≤ 5.0%
pH (in solution)	6.5 - 7.5
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.