Description

1H-Indazole, 6-(Trifluoromethoxy)- is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is valued for its unique molecular scaffold, which incorporates both an indazole core and a trifluoromethoxy substituent, enabling critical modifications in drug discovery and development. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and stability.
• Chemical Biology Probe: Serves as a valuable scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for the synthesis of specialized organic electronic materials or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated indazole derivative.

Basic Information

Product Name	1H-Indazole, 6-(Trifluoromethoxy)-
CAS No.	105391-43-3
Molecular Formula	C8H5F3N2O
Molecular Weight	202.13 g/mol
Synonyms	6-(Trifluoromethoxy)-1H-indazole; 6-(Trifluoromethoxy)indazole; 1H-Indazole-6-ol, trifluoromethyl ether; 6-Trifluoromethoxyindazole; 6-(Trifluoromethoxy)indazole; 105391-43-3; AI3-63100; SCHEMBL2188517
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 6-(Trifluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates for research and regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.