Description

Deacetyltaxol, 7-Epi-10-Oxo-10- (P) is a key taxane derivative and a critical intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in its role as a versatile building block for advanced research and development in oncology and other therapeutic areas. This high-purity intermediate is essential for pharmaceutical manufacturers, research institutions, and biotechnology companies engaged in the development of novel chemotherapeutic agents and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated synthetic precursor in the multi-step production of paclitaxel analogs and other taxane-based chemotherapeutic agents.
• Oncology Research: A vital reference standard and building block in academic and industrial research programs focused on understanding and improving the efficacy and safety of taxane drugs.
• Process Chemistry Development: Used by process chemists to develop and optimize scalable synthetic routes for complex natural product derivatives.
• Bioactive Molecule Synthesis: Serves as a starting material for the synthesis of novel chemical entities with potential biological activity beyond oncology.
• Analytical Standard: Employed as a high-purity standard in analytical methods (e.g., HPLC, LC-MS) for quality control and quantification of related substances in pharmaceutical products.

Basic Information

Product Name	Deacetyltaxol, 7-Epi-10-Oxo-10- (P)
CAS No.	105377-71-7
Molecular Formula	C45H49NO14
Molecular Weight	827.88 g/mol
Synonyms	7-Epi-10-oxo-10-deacetylpaclitaxel; 10-Deacetyl-7-epi-10-oxopaclitaxel; 7-Epi-10-oxo-10-deacetyltaxol; 10-Oxo-7-epitaxol; Paclitaxel Impurity F (EP); Taxane Derivative 105377-71-7; 7-Epi-10-oxo-DAP
EINECS	Contact for details

Quality Control

Our Deacetyltaxol, 7-Epi-10-Oxo-10- (P) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.