Description

Prepro-Von Willebrand Factor is a high-purity recombinant protein that serves as the precursor to the mature Von Willebrand Factor, a critical glycoprotein in hemostasis. This product is essential for advanced research and development in the fields of hematology, coagulation science, and biopharmaceutical manufacturing. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biopharmaceutical companies engaged in developing therapies for bleeding disorders like von Willebrand disease.

Application

• Biomedical Research: Used as a critical reagent in fundamental studies of blood coagulation mechanisms, platelet adhesion, and vascular biology.
• Diagnostic Development: Serves as a reference standard or key component in the calibration and validation of immunoassays and coagulation tests for von Willebrand disease.
• Therapeutic Protein Production: Acts as a starting material or intermediate in the research and development of recombinant therapeutic proteins for treating coagulation factor deficiencies.
• Cell Culture & Biotechnology: Employed in specialized cell culture applications and protein engineering studies requiring defined, high-quality protein substrates.
• Quality Control & Standardization: Used by pharmaceutical and diagnostic manufacturers as an in-house control standard to ensure batch-to-b consistency of their products.

Basic Information

Product Name	Prepro-Von Willebrand Factor
CAS No.	105287-72-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Prepro-VWF; von Willebrand Factor Precursor; Pre-pro-Von Willebrand Factor; VWF Precursor; Coagulation Factor VIII VWF; F8VWF; Prepro-Von Willebrand Antigen; Recombinant Prepro-VWF
EINECS	Contact for details

Quality Control

Our Prepro-Von Willebrand Factor is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing specific results for purity (by HPLC), identity (by mass spectrometry or immunoassay), and endotoxin levels are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture condensation. For optimal stability, aliquot into single-use quantities to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoassay)	Complies
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Biological Activity	Contact for details
Endotoxin	< 1.0 EU/μg
Moisture (Karl Fischer)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.