Description

Inosine 5'-Triphosphate, Periodate Oxidized Sodium Salt is a chemically modified nucleotide analog where the ribose ring of inosine triphosphate has been selectively cleaved by periodate oxidation. This modification is critical for creating reactive intermediates used in bioconjugation and cross-linking applications. It is an essential reagent for researchers and manufacturers in the fields of biochemistry, molecular biology, and pharmaceutical development, particularly for labeling and modifying nucleic acids and proteins.

Application

• Bioconjugation Chemistry: Key intermediate for the covalent attachment of labels, probes, or other molecules to biomolecules via the reactive aldehyde groups generated from periodate oxidation.
• Nucleic Acid Labeling: Used in the preparation of non-radioactive probes for techniques like fluorescence in situ hybridization (FISH) and microarray analysis.
• Cross-linking Agent: Serves as a homobifunctional cross-linker for studying protein-nucleic acid or protein-protein interactions.
• Enzyme Substrate Analog: Useful in enzymatic studies as an analog for natural nucleotides to investigate enzyme mechanism and inhibition.
• Pharmaceutical Research: Employed in the synthesis of nucleotide-based prodrugs and antiviral compounds.
• Diagnostic Assay Development: Component in the manufacture of diagnostic kits that rely on labeled nucleotides for detection.

Basic Information

Item	Details
Product Name	Inosine 5'-Triphosphate, Periodate Oxidized Sodium Salt
CAS No.	105208-87-5
Molecular Formula	C10H12N4Na3O14P3 (or similar, based on salt form)
Molecular Weight	Contact for details
Synonyms	Periodate-Oxidized Inosine Triphosphate Sodium Salt; Oxidized ITP Sodium Salt; o-ITP Na Salt; 5'-ITP, periodate oxidized, sodium salt; Inosine 5'-triphosphate dialdehyde sodium salt; Inosine triphosphate dialdehyde; ITP dialdehyde sodium salt; 2',3'-Dialdehyde-ITP sodium salt
EINECS	Contact for details

Quality Control

Every batch of Inosine 5'-Triphosphate, Periodate Oxidized Sodium Salt is manufactured and tested under strict quality management protocols. We ensure high purity and consistency suitable for research and diagnostic applications. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0 %
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.