Description

4-Chloro-3-Formyl-Benzonitrile is a high-value aromatic nitrile and aldehyde building block used in advanced organic synthesis. This compound matters for its bifunctional reactivity, where the formyl and cyano groups serve as versatile handles for constructing complex heterocyclic and pharmaceutical intermediates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing chlorinated benzaldehyde or benzonitrile motifs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Ligand and Catalyst Development: Used to prepare specialized chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Functional Material Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex colorants and photostable pigments.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services in fine chemical production.

Basic Information

Product Name	4-Chloro-3-Formyl-Benzonitrile
CAS No.	105191-41-1
Molecular Formula	C8H4ClNO
Molecular Weight	165.58 g/mol
Synonyms	4-Chloro-3-formylbenzonitrile; 3-Cyano-4-chlorobenzaldehyde; 4-Chloro-3-cyanobenzaldehyde; 2-Chloro-5-cyanobenzaldehyde; 5-Cyano-2-chlorobenzaldehyde; 105191-41-1; 4-Chloro-3-formylbenzonitrile; Benzaldehyde, 2-chloro-5-cyano-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Formyl-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for prolonged operations to minimize oxidation risk. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.