Description

Tgf-Alpha CAS NO 105186-99-0 is a high-purity, biologically active peptide belonging to the transforming growth factor family, known for its critical role in cellular signaling and regulation. This compound is essential for advanced research and development in life sciences, where precise molecular tools are required to study complex biological pathways. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in cell biology, oncology research, and therapeutic discovery.

Application

• Biomedical Research: Used as a key reagent in cell culture studies to investigate cell proliferation, differentiation, and apoptosis mechanisms.
• Oncology Studies: Employed in cancer research to explore the role of TGF-α in tumor growth, metastasis, and angiogenesis.
• Signal Transduction Analysis: A vital tool for studying EGFR (Epidermal Growth Factor Receptor) pathway activation and downstream signaling events.
• Drug Discovery & Development: Serves as a reference standard or target molecule in high-throughput screening assays for novel therapeutic candidates.
• Tissue Engineering: Applied in regenerative medicine research to study its effects on stem cell behavior and tissue regeneration.
• Diagnostic Development: Utilized in the development and calibration of immunoassays and biosensors for biomarker detection.

Basic Information

Item	Details
Product Name	Tgf-Alpha
CAS No.	105186-99-0
Molecular Formula	C174H277N51O53S2
Molecular Weight	3967.5 g/mol
Synonyms	Transforming Growth Factor Alpha; TGF-α; TGF Alpha; TGFA; Cell Growth Factor Alpha; Epidermal Growth Factor-like TGF; Sarcoma Growth Factor; Rat Transforming Growth Factor Type Alpha; Human Transforming Growth Factor Alpha; Murine Transforming Growth Factor Alpha
EINECS	Contact for details

Quality Control

Our Tgf-Alpha is manufactured under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry for identity confirmation, and bioactivity assays. A detailed Certificate of Analysis (COA) documenting purity, endotoxin levels, and sterility (where applicable) is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Molecular Weight	3967.5 ± 2 Da
Biological Activity	Determined by cell-based assay
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.