Description

3-Hydroxy-4-Decenoyl-Coenzyme A is a specialized, high-purity biochemical intermediate essential for research in lipid metabolism and enzymology. This compound serves as a critical substrate for studying the activity and inhibition of key enzymes involved in fatty acid β-oxidation pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on metabolic disorders, enzyme kinetics, and the development of novel therapeutic agents.

Application

• Enzymology Research: As a specific substrate for studying dehydrogenases and other enzymes in the fatty acid β-oxidation spiral.
• Metabolic Pathway Analysis: Investigating inborn errors of metabolism, such as defects in mitochondrial fatty acid oxidation.
• Pharmaceutical Development: Used in high-throughput screening (HTS) assays to identify potential inhibitors or modulators of metabolic enzymes for drug discovery.
• Biochemical Reagent: Serves as a key intermediate in the synthesis of more complex labeled compounds for tracer studies.
• Diagnostic Kit Manufacturing: A component in enzymatic assay kits designed to diagnose specific metabolic deficiencies.
• Academic Research: Fundamental studies on Coenzyme A ester chemistry and their role in cellular bioenergetics.

Basic Information

Product Name	3-Hydroxy-4-Decenoyl-Coenzyme A
CAS No.	105181-63-3
Molecular Formula	C₃₁H₅₂N₇O₁₇P₃S
Molecular Weight	919.77 g/mol
Synonyms	3-Hydroxy-4-Decenoyl-CoA; (3R)-3-Hydroxy-4-Decenoyl-Coenzyme A; L-3-Hydroxy-4-Decenoyl-CoA; 3-Hydroxy-trans-2-Decenoyl-Coenzyme A; 3-Hydroxydec-4-enoyl-CoA; CoA C10:1(4); 3-Hydroxy-4-Decenoyl Coenzyme A Lithium Salt; 3-OH-4-Decenoyl-CoA
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Decenoyl-Coenzyme A is manufactured under strict quality-controlled conditions suitable for research applications. Each batch is characterized and tested to ensure identity, purity, and stability. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC, NMR, and MS analyses to confirm compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Tested in enzymatic assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.