Description

(R)-n-(2-Benzoylphenyl)-1-(Phenylmethyl)-2-Pyrrolidinecarboxamide CAS NO 105024-93-9 is a high-purity, chiral pyrrolidinecarboxamide derivative, a crucial building block in advanced pharmaceutical synthesis. Its primary value lies in its role as a key chiral intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries who are developing enantioselective drugs, especially in neurological and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Neurological Drug Research: Used in the synthesis of potential therapeutic agents targeting neurological pathways and receptors.
• Metabolic Disorder Therapeutics: Serves as a building block for compounds under investigation for treating metabolic syndromes.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry R&D: A valuable tool compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for chiral drug candidates.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(R)-n-(2-Benzoylphenyl)-1-(Phenylmethyl)-2-Pyrrolidinecarboxamide
CAS No.	105024-93-9
Molecular Formula	C25H24N2O2
Molecular Weight	384.47 g/mol
Synonyms	(R)-N-(2-Benzoylphenyl)-1-benzyl-2-pyrrolidinecarboxamide; (R)-1-Benzyl-N-(2-benzoylphenyl)pyrrolidine-2-carboxamide; UNII-6V8R1B4V6S; (R)-1-Benzyl-2-[(2-benzoylphenyl)carbamoyl]pyrrolidine; (R)-enantiomer of 1-Benzyl-N-(2-benzoylphenyl)pyrrolidine-2-carboxamide; (2R)-1-Benzyl-N-(2-benzoylphenyl)pyrrolidine-2-carboxamide; Pyrrolidine-2-carboxamide, 1-(phenylmethyl)-N-[2-(phenylcarbonyl)phenyl]-, (2R)-
EINECS	Contact for details

Quality Control

Our (R)-n-(2-Benzoylphenyl)-1-(Phenylmethyl)-2-Pyrrolidinecarboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. All products undergo rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.