Description

2-(4-Bromo-2-Nitrophenyl)Acetonitrile is a versatile brominated nitrophenyl acetonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which provides reactive sites for constructing complex heterocyclic systems and functionalized aromatic compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those containing complex heterocycles like benzimidazoles, quinolines, and indoles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups for structural diversification.
• Dye and Pigment Chemistry: Serves as a precursor for the development of specialized azo dyes and organic pigments due to its nitrophenyl backbone.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials requiring tailored electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) to create biaryl and other complex structures.
• Nitrile Transformation Chemistry: The acetonitrile group can be hydrolyzed to acids, reduced to amines, or converted into tetrazoles, expanding its utility in library synthesis.

Basic Information

Product Name	2-(4-Bromo-2-Nitrophenyl)Acetonitrile
CAS No.	105003-96-1
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	(4-Bromo-2-nitrophenyl)acetonitrile; 2-(4-Bromo-2-nitrophenyl)ethanenitrile; 4'-Bromo-2'-nitrophenylacetonitrile; 2-Nitro-4-bromophenylacetonitrile; α-(4-Bromo-2-nitrophenyl)acetonitrile; 4-Bromo-2-nitrophenylacetonitrile; 105003-96-1; (4-Bromo-2-nitrobenzyl) cyanide
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Nitrophenyl)Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to relevant industry standards, and our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.