Description

Mentholglucuronic Acid Ammonium Salt is a specialized biochemical derivative formed from the conjugation of menthol with glucuronic acid, stabilized as an ammonium salt. This compound is of significant interest in pharmaceutical and biochemical research due to its role as a potential metabolite or analytical reference standard for studying the biotransformation and pharmacokinetics of menthol and related terpenoids. It serves critical needs for researchers and manufacturers in the pharmaceutical, nutraceutical, and flavor/fragrance industries who require high-purity, well-characterized compounds for method development, quality control, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of menthol metabolites in bioanalytical studies, supporting drug development and pharmacokinetic research.
• Metabolite Research: Essential for in vitro and in vivo studies investigating the glucuronidation pathway of menthol, aiding in the understanding of its detoxification and excretion mechanisms.
• Analytical Chemistry: Serves as a critical standard in High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) methods for assay development and validation in quality control laboratories.
• Biochemical Reagent: Employed in enzymatic studies related to UDP-glucuronosyltransferase (UGT) activity and specificity.
• Flavor & Fragrance Analysis: Used in the analysis and quality assurance of menthol-containing products to understand and monitor metabolite profiles.

Basic Information

Product Name	Mentholglucuronic Acid Ammonium Salt
CAS No.	104874-25-1
Molecular Formula	C₁₆H₂₉NO₈ • xNH₃ (Contact for exact stoichiometry)
Molecular Weight	Contact for details
Synonyms	Ammonium Menthol Glucuronate; Menthol Glucuronide Ammonium Salt; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl β-D-Glucopyranosiduronic Acid Ammonium Salt; Menthol β-D-Glucuronide Ammonium Salt; L-Menthol Glucuronate Ammonium; p-Menthan-3-ol Glucuronide Ammonium Salt; Ammonium (1R,2S,5R)-2-(1-Methylethyl)-5-methylcyclohexyl β-D-Glucopyranosiduronate
EINECS	Contact for details

Quality Control

Our Mentholglucuronic Acid Ammonium Salt is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.