Description

5-Carboxy-2-Nitrobenzyl Cyanide is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a nitro group ortho to the benzylic nitrile, makes it a valuable precursor for constructing complex heterocyclic systems and functionalized aromatic compounds. This high-purity building block is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those containing quinoline, quinazoline, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require functionalized benzoic acid derivatives.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other colorants where the nitro and cyano groups contribute to chromophore development.
• Material Science Research: Employed in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	5-Carboxy-2-Nitrobenzyl Cyanide
CAS No.	104825-21-0
Molecular Formula	C9H6N2O4
Molecular Weight	206.16 g/mol
Synonyms	2-Nitro-5-cyanomethylbenzoic Acid; (2-Nitro-5-carboxyphenyl)acetonitrile; 5-Cyano-2-nitrobenzyl Alcohol (oxidized form); 2-Nitro-5-(cyanomethyl)benzoic Acid; α-Cyano-2-nitro-5-methylbenzoic Acid; 5-(Cyanomethyl)-2-nitrobenzoic Acid; 104825-21-0; 2-Nitro-5-carboxyphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 5-Carboxy-2-Nitrobenzyl Cyanide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for use in cGMP-compliant pharmaceutical development and other high-value applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.