Description

n-o-Nps-Dl -Norvaline is a specialized, non-proteinogenic amino acid derivative, widely recognized by its CAS registry number 104809-37-2. This compound is a critical chiral building block and protecting group reagent in advanced organic synthesis, particularly for peptide chemistry. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used as a protected amino acid derivative (with the o-Nitrophenylsulfenyl, Nps, group) for the controlled, sequential assembly of complex peptides.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor in biochemical assays.
• Proteomics & Molecular Biology: Utilized in the design and synthesis of modified peptides for studying protein structure, function, and interactions.
• Fine Chemical Synthesis: Acts as a versatile building block for creating custom-designed molecules in agrochemical and material science research.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	n-o-Nps-Dl -Norvaline
CAS No.	104809-37-2
Molecular Formula	C₁₁H₁₄N₂O₄S
Molecular Weight	270.31 g/mol
Synonyms	DL-2-Amino-N-(2-nitrophenylsulfenyl)pentanoic acid; N-(2-Nitrophenylthio)norvaline; Norvaline, N-o-nitrophenylsulfenyl-; NPS-Norvaline; o-Nps-DL-Norvaline; 2-[[(2-Nitrophenyl)sulfanyl]amino]pentanoic acid; (RS)-2-[[(2-Nitrophenyl)sulfanyl]amino]pentanoic acid
EINECS	Contact for details

Quality Control

Our n-o-Nps-Dl -Norvaline is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the exacting standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.