Description

(S)-4-Methyl-2,2,2-Triphenyl-2Lambda5-[1,3,2]Dioxaphospholane CAS NO 104762-38-1 is a high-purity, chiral organophosphorus compound widely utilized as a key intermediate and chiral auxiliary in asymmetric synthesis. Its primary value lies in its ability to induce stereoselectivity in critical bond-forming reactions, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral building blocks.

Application

• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in transition metal-catalyzed reactions, such as hydrogenation and cross-coupling.
• Pharmaceutical Intermediates: A critical building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides.
• Catalyst Development: Serves as a precursor or component in the development of novel chiral catalysts.
• Material Science Research: Applied in the synthesis of chiral polymers or advanced organic materials with specific optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	(S)-4-Methyl-2,2,2-Triphenyl-2Lambda5-[1,3,2]Dioxaphospholane
CAS No.	104762-38-1
Molecular Formula	C22H21O2P
Molecular Weight	348.38 g/mol
Synonyms	(S)-4-Methyl-2,2,2-triphenyl-1,3,2-dioxaphospholane; (S)-4-Methyl-2,2,2-triphenyl-1,3,2-dioxaphospholane 2-oxide; (S)-Methyl-TRIP; (S)-Me-TRIP; (S)-TRIP; (S)-2,2,2-Triphenyl-4-methyl-1,3,2-dioxaphospholane; (S)-4-Methyl-2,2,2-triphenyl-[1,3,2]dioxaphospholane 2-oxide
EINECS	Contact for details

Quality Control

Our (S)-4-Methyl-2,2,2-Triphenyl-2Lambda5-[1,3,2]Dioxaphospholane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.