Description

L-Alanine, n-Hydroxy-, Methyl Ester (9Ci) is a specialized amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate, enabling the construction of complex molecules with high stereochemical fidelity. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, bioactive peptides, and fine chemicals. Its defined structure and purity are essential for ensuring reproducibility and efficacy in downstream applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other enzyme-targeted therapies.
• Peptide Synthesis: Used as a protected or modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce specific functional groups or alter peptide properties.
• Biochemical Research: Employed in enzymatic studies and as a precursor for synthesizing enzyme substrates, inhibitors, or fluorescent probes for biological assays.
• Agrochemical Development: Acts as an intermediate in the research and production of advanced, chiral herbicides and plant growth regulators.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural product analogs, specialty polymers, and ligands for catalysis.

Basic Information

Product Name	L-Alanine, n-Hydroxy-, Methyl Ester (9Ci)
CAS No.	104739-54-0
Molecular Formula	C₄H₉NO₃
Molecular Weight	119.12 g/mol
Synonyms	Methyl N-hydroxy-L-alaninate; L-Alanine, N-hydroxy-, methyl ester; Methyl (2S)-2-(hydroxyamino)propanoate; (S)-Methyl 2-(hydroxyamino)propanoate; N-Hydroxy-L-alanine methyl ester; Alanine, N-hydroxy-, methyl ester, L-; Methyl ester of N-hydroxy-L-alanine
EINECS	Contact for details

Quality Control

Our L-Alanine, n-Hydroxy-, Methyl Ester (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediate applications, ensuring traceability and documentation meet industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.