Description

Farnesyl Diphosphate (Fpp) is a critical 15-carbon isoprenoid intermediate in the mevalonate pathway, serving as the universal precursor for the biosynthesis of sesquiterpenes, sterols, and other essential biomolecules. Its precise chemical structure makes it indispensable for enzymatic studies and the synthesis of complex natural products. This high-purity biochemical is primarily utilized by researchers and manufacturers in pharmaceutical development, biotechnology, and synthetic biology for investigating metabolic pathways and creating novel compounds.

Application

• Enzymology & Biochemical Research: Essential substrate for studying farnesyltransferase and other prenyltransferase enzymes involved in protein prenylation and terpenoid biosynthesis.
• Pharmaceutical Intermediate: Key building block in the research and development of therapeutics targeting cholesterol synthesis, cancer (via Ras protein inhibition pathways), and parasitic diseases.
• Synthetic Biology: Used in engineered metabolic pathways within microorganisms for the microbial production of high-value terpenoids and isoprenoids.
• Natural Product Synthesis: Serves as a precursor in the chemical and enzymatic synthesis of sesquiterpenes, a large class of plant-derived compounds with various biological activities.
• Cell Signaling Studies: Employed in research focused on understanding the role of protein farnesylation in cell growth, differentiation, and signal transduction.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quantification and method validation in biological matrices.

Basic Information

Product Name	Farnesyl Diphosphate (Fpp)
CAS No.	104715-19-7
Molecular Formula	C15H28O7P2
Molecular Weight	382.32 g/mol
Synonyms	Farnesyl Diphosphate; Farnesyl Pyrophosphate; FPP; (2E,6E)-Farnesyl Diphosphate; (2E,6E)-Farnesyl Pyrophosphate; trans,trans-Farnesyl Diphosphate; all-trans-Farnesyl Diphosphate; Nerolidyl Diphosphate Isomer; Isoprenoid Pyrophosphate
EINECS	Contact for details

Quality Control

Our Farnesyl Diphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot contents to minimize repeated freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water or suitable aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.