Description

Factor XIII Subunit A is a crucial coagulation factor protein that plays a vital role in the final stage of the blood clotting cascade by cross-linking fibrin polymers to stabilize clots. This high-purity biochemical is essential for research, diagnostic, and therapeutic development in the life sciences sector. It is primarily utilized by pharmaceutical R&D teams, clinical diagnostic manufacturers, and academic researchers focused on hemostasis, thrombosis, and related hematological disorders.

Application

• Pharmaceutical Research & Development: Used as a key active ingredient or reference standard in the development of novel therapeutics for bleeding disorders, wound healing, and tissue engineering.
• In Vitro Diagnostic (IVD) Manufacturing: Serves as a critical component in the production of diagnostic assay kits, calibrators, and controls for measuring Factor XIII activity or antigen levels in clinical laboratories.
• Biochemical Research: Employed in enzymatic studies, structural biology, and mechanism-of-action research to understand the role of Factor XIIIa in fibrin stabilization and cellular processes.
• Quality Control & Standardization: Acts as a reference material for the quality control and potency assessment of plasma-derived or recombinant Factor XIII concentrates.
• Cell Culture & Tissue Engineering: Investigated for its potential application in modifying extracellular matrices to enhance cell adhesion and scaffold stability.

Basic Information

Product Name	Factor XIII Subunit A
CAS No.	104641-95-4
Molecular Formula	Contact for details
Molecular Weight	~83,000 Da (Apolypeptide chain)
Synonyms	Fibrin-Stabilizing Factor A Subunit
Coagulation Factor XIII A Chain
F13A1
Protein-glutamine γ-glutamyltransferase A chain
Transglutaminase Plasma Factor, A Subunit
Recombinant Human Factor XIII A-subunit
rF XIII-A
EINECS	Contact for details

Quality Control

Our Factor XIII Subunit A is produced and tested under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, activity assays, and endotoxin level verification, to ensure it meets the exacting standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, potency, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccated conditions after opening.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Complies
Purity (HPLC)	≥ 95%
Specific Activity	Contact for details
Protein Content (Biuret)	Contact for details
Endotoxin (LAL)	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.