Description

Activins CAS NO 104625-48-1 refers to a class of signaling proteins belonging to the transforming growth factor-beta (TGF-β) superfamily. These proteins play a critical role in regulating a wide array of cellular processes, including proliferation, differentiation, and apoptosis. They are of significant interest to researchers and developers in the fields of cell biology, regenerative medicine, and pharmaceutical development for their potential in tissue engineering and therapeutic applications.

Application

• Biomedical Research: Used as a key reagent in stem cell differentiation studies, particularly for directing cell fate towards specific lineages.
• Drug Discovery & Development: Investigated as a potential therapeutic target or agent for conditions related to cell growth and repair.
• Tissue Engineering: Incorporated into scaffolds and culture systems to promote the growth and specialization of specific cell types for regenerative medicine.
• Cell Culture & Assay Development: Essential component in specialized cell culture media for maintaining or differentiating primary cells and cell lines.
• Diagnostic Development: Utilized in the development of assays to measure biological activity or levels in research samples.

Basic Information

Product Name	Activins
CAS No.	104625-48-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Activin A; Activin AB; Activin B; Activin Beta A chain; FRP; FSH-releasing protein; EDF; Erythroid differentiation factor; XTC-MIF
EINECS	Contact for details

Quality Control

Our Activins are produced and tested under stringent conditions to ensure high biological activity, purity, and batch-to-batch consistency. Quality is verified through a series of analytical methods including SDS-PAGE, HPLC, and bioactivity assays. A comprehensive Certificate of Analysis (COA) detailing purity, endotoxin levels, and biological activity is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled in a dry environment and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Complies
Endotoxin Level	< 1.0 EU/μg
Biological Activity (Cell-based assay)	Reported on COA
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.