Description

Hepatitis B Virus Pre-S Region (120-145) CAS NO 104504-34-9 is a synthetic peptide fragment corresponding to a specific sequence within the Pre-S region of the Hepatitis B Virus surface antigen. This high-purity biochemical is critical for advanced virology research, vaccine development, and diagnostic assay design. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic research institutions focused on hepatitis B immunology and therapeutic discovery.

Application

• Immunological Research: Used as a defined antigen to study the host immune response, including B-cell and T-cell epitope mapping for Hepatitis B Virus.
• Vaccine Development: Serves as a key component in the research and development of next-generation peptide-based or multi-epitope vaccines against HBV.
• Diagnostic Assay Production: Employed as a coating antigen or standard in the manufacture of ELISA kits and other immunoassays for the detection of anti-Pre-S antibodies.
• Antibody Characterization: Essential for the screening, purification, and specificity testing of monoclonal and polyclonal antibodies targeting the Pre-S region.
• Biomarker Studies: Facilitates research into viral entry mechanisms and the role of the Pre-S domain in infection and disease progression.
• Quality Control Reference: Acts as a critical reference standard for the quality assurance of diagnostic products and biological reagents.

Basic Information

Item	Details
Product Name	Hepatitis B Virus Pre-S Region (120-145)
CAS No.	104504-34-9
Molecular Formula	C134H215N39O43S
Molecular Weight	3027.5 g/mol
Synonyms	HBV Pre-S (120-145) peptide; Hepatitis B virus genotype D surface antigen PreS region 120-145; PreS1 peptide (120-145); HBsAg Pre-S1 fragment; Synthetic HBV Pre-S antigen; PreS region epitope; LHBV_PRES (120-145); [Asn120,Ser121,Thr122,Leu123,His124,Ser125,Pro126,Ser127,Ser128,Thr129,Ser130,Gly131,Pro132, Gly133,Asn134,Leu135,Thr136,Ser137,Thr138,Gln139,Gly140,Val141,Arg142,Gln143,Leu144,Tyr145]-peptide
EINECS	Contact for details

Quality Control

Every batch of Hepatitis B Virus Pre-S Region (120-145) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous purity and identity verification to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, sequence verification, and analytical data (including HPLC and MS) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a dry environment before opening to minimize moisture absorption. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Sequence	NSTLHSPSSTSGPGNLTS TQGVRQLY
Molecular Weight	3027.5 ± 1.0 Da (by MS)
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.