Description

Glicentin (1-16) is a defined peptide fragment of the proglucagon-derived hormone, glicentin. This high-purity reference standard is critical for metabolic and gastrointestinal research, enabling precise analytical and biological studies. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on diabetes, obesity, and enteroendocrine function.

Application

• Biochemical Research: Used as a reference standard in the study of proglucagon processing and peptide hormone biology.
• Immunoassay Development: Serves as a critical antigen for the production and calibration of specific antibodies and ELISA kits.
• Metabolic Studies: Applied in in vitro and in vivo research to investigate its role in glucose homeostasis and insulin secretion.
• Gastrointestinal Physiology: Employed to explore the functions of gut-derived hormones on intestinal motility and mucosal growth.
• Pharmaceutical Screening: Acts as a tool compound in drug discovery programs targeting glucagon-like peptide-1 (GLP-1) related pathways.
• Quality Control: Functions as a system suitability standard in analytical methods (e.g., HPLC, LC-MS) for related peptide pharmaceuticals.

Basic Information

Product Name	Glicentin (1-16)
CAS No.	104504-00-9
Molecular Formula	C81H125N23O23S
Molecular Weight	1820.06 g/mol
Synonyms	Glicentin 1-16; Glicentin (1-16) amide; PG 33-69; Proglucagon 33-69; Oxyntomodulin (1-16); Enteroglucagon fragment 1-16; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-NH2; [His1, Ser16]-Glicentin (1-16) amide
EINECS	Contact for details

Quality Control

Our Glicentin (1-16) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum confirms molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.