Description

4-Cyano-2-Methoxybenzyl Bromide is a versatile and high-value brominated aromatic building block, essential for constructing complex molecular architectures. Its core value lies in the reactive benzyl bromide moiety and the electron-withdrawing cyano group, which facilitate selective nucleophilic substitution and further functionalization. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides by introducing the methoxybenzyl moiety into active molecules.
• Ligand and Catalyst Development: Serves as a starting material for preparing specialized phosphine or nitrogen-based ligands for transition metal catalysis.
• Material Science Research: Building block for organic semiconductors, liquid crystals, and photoactive polymers due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.
• Academic & R&D Laboratories: Employed in methodological studies for new C-C and C-N bond-forming cross-coupling reactions.

Basic Information

Item	Details
Product Name	4-Cyano-2-Methoxybenzyl Bromide
CAS No.	104436-60-4
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	2-Methoxy-4-cyanobenzyl Bromide; (4-Cyano-2-methoxyphenyl)methyl Bromide; α-Bromo-2-methoxy-4-cyanotoluene; 4-Cyanoveratryl Bromide; 2-Methoxy-4-cyanobenzyl Bromide; 4-Cyano-o-anisyl Bromide; Bromomethyl-2-methoxy-4-cyanobenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Cyano-2-Methoxybenzyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.