Description

3-Chloro-2-Fluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for fine chemical manufacturers offering bespoke synthesis services to global clients.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Chloro-2-Fluorobenzamide
CAS No.	104326-94-5
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Fluoro-3-chlorobenzamide; 3-Chloro-2-fluorobenzoic acid amide; Benzamide, 3-chloro-2-fluoro-; 3-Chloro-2-fluorobenzenecarboxamide; 104326-94-5; 3-Chloro-2-fluoro-benzamide; 2-Fluoro-3-chloro-benzamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorobenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.