Description

(R)-4-(Benzyloxy)-3-Methylbutanenitrile is a chiral nitrile building block of significant importance in asymmetric synthesis. This compound matters as a key intermediate for the production of high-value active pharmaceutical ingredients (APIs) and fine chemicals, enabling the construction of complex molecules with defined stereochemistry. Pharmaceutical R&D and fine chemical manufacturers need it for developing novel therapeutics, particularly in areas requiring precise chiral control.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various APIs, including potential antiviral and cardiovascular drugs.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds for agrochemicals and specialty materials.
• Organic Synthesis Building Block: Serves as a versatile precursor for the introduction of the (R)-4-(benzyloxy)-3-methylbutyl moiety into target molecules.
• Catalyst and Ligand Development: Employed in research for creating novel chiral catalysts and ligands used in transition metal catalysis.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	(R)-4-(Benzyloxy)-3-Methylbutanenitrile
CAS No.	104265-24-9
Molecular Formula	C₁₂H₁₅NO
Molecular Weight	189.25 g/mol
Synonyms	(R)-4-(Benzyloxy)-3-methylbutyronitrile; (3R)-4-(Benzyloxy)-3-methylbutanenitrile; (R)-4-(Benzyloxy)-3-methylbutyronitrile; (R)-3-Methyl-4-(phenylmethoxy)butanenitrile; Butanenitrile, 4-(benzyloxy)-3-methyl-, (3R)-; (R)-4-(Benzyloxy)-3-methylbutyronitrile; (R)-O-Benzyl-3-methyl-4-hydroxybutyronitrile derivative
EINECS	Contact for details

Quality Control

Our (R)-4-(Benzyloxy)-3-Methylbutanenitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.