Description

Pth (1-38) (Human) is a synthetic peptide fragment corresponding to the first 38 amino acids of the human parathyroid hormone. This bioactive sequence is a critical research tool for studying calcium metabolism, bone physiology, and endocrine signaling pathways. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focused on metabolic disorders and drug discovery.

Application

• Biomedical Research: Fundamental studies on parathyroid hormone (PTH) receptor binding, activation mechanisms, and downstream signaling cascades.
• Drug Discovery & Development: Used as a reference standard, competitive ligand, or lead compound in the screening and development of novel therapeutics for osteoporosis and hyperparathyroidism.
• In Vitro & Ex Vivo Assays: Functional assays to evaluate biological activity in cell-based systems and tissue cultures.
• Analytical Standard: Serves as a high-purity calibrant for quantitative analytical methods such as HPLC and mass spectrometry.
• Peptide Chemistry Studies: A model compound for studying peptide stability, formulation, and delivery strategies.

Basic Information

Item	Detail
Product Name	Pth (1-38) (Human)
CAS No.	104218-12-4
Molecular Formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Molecular Weight	≈ 4507.1 g/mol
Synonyms	Parathyroid Hormone (1-38), Human; hPTH (1-38); PTH 1-38; Parathyrin (1-38); Teriparatide Fragment (1-38); PTH Human 1-38; CAS 104218-12-4
EINECS	Contact for details

Quality Control

Our Pth (1-38) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. A detailed Certificate of Analysis (COA) is provided, reporting results from HPLC, MS, and amino acid analysis. We support research requiring high-purity, well-characterized peptides for reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.