Description

Phe-Leu-Arg-Phe Amide is a synthetic peptide sequence of significant interest in biochemical and pharmacological research. This compound serves as a valuable tool for studying enzyme-substrate interactions, particularly with proteases like furin and other proprotein convertases. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in neuroscience, cardiovascular research, and the development of therapeutic agents. Its defined structure makes it an essential reference standard and substrate for high-precision analytical work.

Application

• Biochemical Research: Used as a specific substrate for studying the activity and kinetics of serine proteases and proprotein convertases.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and validation of novel protease inhibitors.
• Neuroscience Studies: Applied in research related to neuropeptide processing and signaling pathways.
• Enzyme Characterization: Employed to determine the specificity and catalytic efficiency of various proteolytic enzymes in vitro.
• Quality Control Standard: Used as an analytical reference standard in peptide synthesis quality assurance and purity testing.
• Academic Research: A critical reagent for university and institutional labs focusing on peptide chemistry and molecular biology.

Basic Information

Product Name	Phe-Leu-Arg-Phe Amide
CAS No.	104180-32-7
Molecular Formula	C34H51N9O5
Molecular Weight	665.83 g/mol
Synonyms	F-L-R-F-NH2; Phe-Leu-Arg-Phe-NH2; H-Phe-Leu-Arg-Phe-NH2; F-L-R-F Amide; Tetrapeptide amide F-L-R-F; F-L-R-F Peptide Amide; FLRFamide (mammalian); Proprotein Convertase Substrate
EINECS	Contact for details

Quality Control

Our Phe-Leu-Arg-Phe Amide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.