Description

2-(3-Methoxy-4-Nitrophenyl)Acetonitrile is a specialized aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both methoxy and nitro substituents, makes it a versatile intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex molecules for drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Dye and Pigment Manufacturing: Used in the production of advanced colorants and functional dyes due to its nitro-aromatic core.
• Material Science Research: Intermediate for developing organic semiconductors, liquid crystals, and other advanced polymeric materials.
• Chemical Research & Development: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	2-(3-Methoxy-4-Nitrophenyl)Acetonitrile
CAS No.	104103-16-4
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	(3-Methoxy-4-nitrophenyl)acetonitrile; 2-(3-Methoxy-4-nitrophenyl)ethanenitrile; 4-Nitro-3-methoxyphenylacetonitrile; 3-Methoxy-4-nitrophenylacetonitrile; 104103-16-4; Acetonitrile, 2-(3-methoxy-4-nitrophenyl)-; NSC 405124
EINECS	Contact for details

Quality Control

Our production of 2-(3-Methoxy-4-Nitrophenyl)Acetonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability for your critical synthesis workflows. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.