Description

4-(Trifluoromethoxy)Phenacyl Bromide is a high-value organobromine building block characterized by its phenacyl bromide core and trifluoromethoxy substituent. This compound is essential for introducing the phenacyl bromide moiety into target molecules, which is a versatile handle for further functionalization in complex organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

This specialized reagent serves as a key intermediate in various synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Precursor: Used in the synthesis of monomers and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Acts as a starting material for creating photoactivatable or affinity-based probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenacyl Bromide
CAS No.	103962-10-3
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethanone; 1-(4-Trifluoromethoxyphenyl)-2-bromoethanone; 4-(Trifluoromethoxy)phenacyl bromide; α-Bromo-4-(trifluoromethoxy)acetophenone; p-Trifluoromethoxyphenacyl bromide; 2-Bromo-4'-(trifluoromethoxy)acetophenone; TFMPAB
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenacyl Bromide is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, GC, NMR, and IR spectroscopy. Our quality assurance system is designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.