Description

1-Iodo-4-(trifluoromethoxy)benzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a trifluoromethoxy group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures for drug discovery and development.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Functional Material Research: Employed in academic and industrial R&D for synthesizing novel ligands, polymers, and specialty chemicals with tailored properties.
• Fluorine Chemistry: Acts as a stable source of a fluorinated aromatic moiety for introducing the trifluoromethoxy group into more complex molecular architectures.

Basic Information

Product Name	1-Iodo-4-(trifluoromethoxy)benzene
CAS No.	103962-05-6
Molecular Formula	C7H4F3IO
Molecular Weight	287.01 g/mol
Synonyms	4-Iodo-1-(trifluoromethoxy)benzene; p-(Trifluoromethoxy)iodobenzene; 1-Iodo-4-(trifluoromethoxy)benzene; 4-(Trifluoromethoxy)phenyl iodide; Iodobenzene, 4-(trifluoromethoxy)-; α,α,α-Trifluoro-p-iodoanisole
EINECS	Contact for details

Quality Control

Our 1-Iodo-4-(trifluoromethoxy)benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.