Description

n-Adamantan-2-Yl-2-Chloro-Acetamide is a specialized fine chemical intermediate featuring a unique adamantane backbone functionalized with a chloroacetamide group. This molecular architecture is of significant interest for its potential to impart rigidity and lipophilicity in advanced pharmaceutical and agrochemical synthesis. It is primarily sought after by research and development chemists and process scale-up teams in the life sciences sector. The compound serves as a critical building block for creating novel active ingredients with enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, viral infections, or requiring protease inhibition.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, or insecticides where the adamantane moiety can enhance environmental persistence and efficacy.
• Material Science: Potential monomer or cross-linking agent for creating high-performance polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tools to study enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	n-Adamantan-2-Yl-2-Chloro-Acetamide
CAS No.	103951-51-5
Molecular Formula	C₁₂H₁₈ClNO
Molecular Weight	227.73 g/mol
Synonyms	2-Chloro-N-(2-adamantyl)acetamide; N-(2-Adamantyl)-2-chloroacetamide; 2-Adamantylamino-2-oxoethyl chloride; 1-(2-Chloroacetyl)adamantane; 2-Chloro-N-tricyclo[3.3.1.1³,⁷]dec-2-ylacetamide; (2-Adamantyl)carbamoylmethyl chloride; Acetamide, 2-chloro-N-(2-adamantyl)-
EINECS	Contact for details

Quality Control

Every batch of n-Adamantan-2-Yl-2-Chloro-Acetamide is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.