Description

n-(8-Aminooctyl)-5-Iodonaphthalene-1-Sulfonamide is a specialized organic compound featuring a naphthalene sulfonamide core functionalized with an aminoalkyl chain and an iodine substituent. This unique molecular architecture makes it a valuable intermediate and research tool, particularly in the development of fluorescent probes and photoaffinity labels for biochemical studies. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors. Its utility stems from its ability to act as a versatile scaffold for targeting and labeling biomolecules.

Application

• Fluorescent Probe Synthesis: Key intermediate for creating site-specific fluorescent labels used in cellular imaging and protein localization studies.
• Photoaffinity Labeling: Serves as a precursor for photoactivatable cross-linkers to study protein-protein and protein-ligand interactions.
• Bioconjugation Chemistry: The amino group enables coupling to peptides, proteins, or other biomolecules for diagnostic and therapeutic agent development.
• Chemical Biology Research: Used as a tool compound in academic and industrial R&D for investigating enzyme mechanisms and receptor binding sites.
• Material Science: Potential building block for advanced organic materials and polymers with specific optical or electronic properties.
• Pharmaceutical Intermediate: Employed in the synthetic pathways for novel drug candidates, especially those targeting neurological or oncological pathways.

Basic Information

Product Name	n-(8-Aminooctyl)-5-Iodonaphthalene-1-Sulfonamide
CAS No.	103771-14-8
Molecular Formula	C18H25IN2O2S
Molecular Weight	484.37 g/mol
Synonyms	5-Iodo-N-(8-aminooctyl)naphthalene-1-sulfonamide; 8-[(5-Iodo-1-naphthyl)sulfonyl]aminooctylamine; 1,5-IAEDANS precursor; N-(8-Aminooctyl)-5-iodo-1-naphthalenesulfonamide; 5-Iodo-1-naphthalenesulfonamide, N-(8-aminooctyl)-; Aminoalkylated iodonaphthalene sulfonamide; ANS derivative; Fluorescent sulfonamide intermediate
EINECS	Contact for details

Quality Control

Our n-(8-Aminooctyl)-5-Iodonaphthalene-1-Sulfonamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.