Description

n-(tert-Butyl)-2-Iodoacetamide is a specialized halogenated acetamide derivative, serving as a versatile alkylating agent and a key synthetic intermediate in advanced organic chemistry. Its value lies in the reactivity of the iodoacetamide moiety, which is crucial for introducing functional groups or creating molecular linkages under controlled conditions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing molecules with tertiary-butyl and acetamide functionalities.
• Bioconjugation Reagent: Acts as an alkylating agent for modifying proteins, peptides, or other biomolecules via reaction with thiol groups (cysteine residues).
• Agrochemical Synthesis: Serves as a building block in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the synthesis of functional polymers, dendrimers, or organic frameworks that require precise molecular architecture.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and metabolic pathways.
• Cross-linking Agent: Applied in biochemical research for creating covalent cross-links between biomolecules to study interactions or stabilize structures.

Basic Information

Product Name	n-(tert-Butyl)-2-Iodoacetamide
CAS No.	103615-48-1
Molecular Formula	C6H12INO
Molecular Weight	241.07 g/mol
Synonyms	2-Iodo-N-(tert-butyl)acetamide; N-(1,1-Dimethylethyl)-2-iodoacetamide; N-tert-Butyl-2-iodoacetamide; 2-Iodo-N-(2-methyl-2-propanyl)acetamide; tert-Butyl iodoacetamide; Iodoacetic acid tert-butylamide; Acetamide, 2-iodo-N-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-2-Iodoacetamide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.