Description

L-Phenylalanine, n-Acetyl-2-Chloro- CAS NO 103522-34-5 is a chemically modified derivative of the essential amino acid L-Phenylalanine, featuring acetylation and chlorination at specific positions. This specialized compound serves as a crucial chiral building block and synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex bioactive molecules, including potential peptide-based therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in peptide and protease inhibitor drug discovery.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate enzyme mechanisms and protein interactions.
• Peptide Synthesis: Serves as a protected or modified amino acid residue in solid-phase and solution-phase peptide synthesis for creating custom peptide sequences.
• Agrochemical Development: Intermediate in the synthesis of advanced, chiral agrochemicals such as herbicides and plant growth regulators.
• Fine Chemical Production: Building block for manufacturing specialized fine chemicals, dyes, and advanced materials requiring specific stereochemistry.
• Academic & Institutional R&D: Essential reagent for universities and research institutions conducting studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	L-Phenylalanine, n-Acetyl-2-Chloro- CAS NO 103522-34-5
CAS No.	103522-34-5
Molecular Formula	C11H12ClNO3
Molecular Weight	241.67 g/mol
Synonyms	N-Acetyl-2-chloro-L-phenylalanine; (2S)-2-Acetamido-3-(2-chlorophenyl)propanoic acid; 2-Chloro-N-acetyl-L-phenylalanine; L-2-Chlorophenylalanine, N-acetyl-; Ac-2-Cl-Phe-OH; N-Acetyl-O-chloro-L-phenylalanine; N-Acetyl-2-chlorophenylalanine; 2-Chloro-N-acetylphenylalanine
EINECS	Contact for details

Quality Control

Every batch of L-Phenylalanine, n-Acetyl-2-Chloro- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, with typical purity levels meeting or exceeding 97% (HPLC). A Certificate of Analysis (COA) detailing specific results for assay, chiral purity, and related substances is available for each lot upon request. Our quality commitment supports applications requiring high-purity research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.