Description

Snake Venom Protein C Activator (Protac®) is a highly purified serine protease enzyme derived from the venom of the Southern copperhead (*Agkistrodon contortrix contortrix*). This compound serves as a critical biochemical tool for the specific and efficient activation of Protein C in plasma, a key regulator of blood coagulation. It is essential for researchers and manufacturers in hemostasis and thrombosis diagnostics, anticoagulant drug development, and clinical research requiring precise control of the protein C pathway.

Application

• Diagnostic Reagent Manufacturing: Core component in commercial kits for the quantitative determination of Protein C activity and antigen in human plasma.
• Biomedical Research: Used in in vitro studies to investigate the protein C anticoagulant pathway, thrombotic disorders, and sepsis.
• Pharmaceutical Development: A vital reagent in the screening and quality control of novel anticoagulant and antithrombotic therapeutics.
• Clinical Laboratory Testing: Employed in hospital and reference labs for the diagnosis of hereditary or acquired Protein C deficiency.
• Coagulation Factor Analysis: Tool for studying interactions between Protein C, thrombin, thrombomodulin, and other factors in the coagulation cascade.
• Standardization and Calibration: Used to prepare reference standards and calibrators for diagnostic equipment and assays.

Basic Information

Product Name	Snake Venom Protein C Activator
CAS No.	103469-93-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Protac®; Agkistrodon contortrix contortrix Venom Protein C Activator; Protein C Activator from Agkistrodon contortrix venom; ACC-C; Activated Protein C (APC) Generating Enzyme; Serine Protease ACC-C; Coagulation Factor XIV (historical).
EINECS	Contact for details

Quality Control

Our Snake Venom Protein C Activator is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to rigorous quality testing, including assessment of specific activity, purity analysis, and functional validation in Protein C activation assays. A comprehensive Certificate of Analysis (COA) detailing purity, activity (IU/mg), and absence of interfering proteases is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Functional)	Activates Human Protein C specifically
Specific Activity	> 3000 IU/mg protein
Purity (SDS-PAGE)	> 95%
Protein Content (Biuret)	Contact for details
Solubility	Soluble in water or buffer
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.