Description

Cyclopropanecarboxylic Acid, 1-Amino-2,3-Dimethyl-, (1Alpha,2Alpha,3Beta)- (9Ci) is a high-purity, stereochemically defined cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique constrained ring structure and functional groups make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane ring can contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Peptidomimetics and Bioisosteres: The rigid cyclopropane scaffold is employed to replace peptide bonds or other moieties in drug design to improve pharmacokinetic properties.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specialized thermal or mechanical properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2,3-Dimethyl-, (1Alpha,2Alpha,3Beta)- (9Ci)
CAS No.	103348-90-9
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1α,2α,3β)-1-Amino-2,3-dimethylcyclopropanecarboxylic acid; 1-Amino-2,3-dimethylcyclopropanecarboxylic acid (1α,2α,3β)-; (1R,2R,3S)-1-Amino-2,3-dimethylcyclopropanecarboxylic acid; trans-1-Amino-2,3-dimethylcyclopropanecarboxylic acid; 2,3-Dimethyl-1-aminocyclopropanecarboxylic acid; Amino-dimethylcyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2,3-Dimethyl-, (1Alpha,2Alpha,3Beta)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.