Description

2-Fluoro-5-Bromoanisole is a versatile halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and bromine substituents on the aromatic ring, which enables precise structural modifications for creating complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and brominated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille), enabling the construction of complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where halogen atoms influence color properties and lightfastness.

Basic Information

Product Name	2-Fluoro-5-Bromoanisole
CAS No.	103291-07-2
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	1-Bromo-4-fluoro-2-methoxybenzene; 5-Bromo-2-fluoroanisole; 2-Fluoro-5-bromomethoxybenzene; 2-Methoxy-4-bromofluorobenzene; 4-Bromo-2-fluoroanisole; Anisole, 2-fluoro-5-bromo-; Benzene, 1-bromo-4-fluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Bromoanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Purity (HPLC/GC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.