Description

3,N4-Ethenocytidine 5'-Triphosphate*Sodium is a chemically modified nucleotide triphosphate analog. This compound is of significant value in biochemical research for studying nucleic acid structure, function, and damage. It is primarily utilized by researchers in molecular biology, enzymology, and toxicology to investigate mutagenesis and DNA adduct formation.

Application

• Biochemical Research: Used as a substrate analog to study the activity and specificity of DNA/RNA polymerases and other nucleotide-processing enzymes.
• Mutagenesis Studies: Employed to investigate the mechanisms of mutagenesis and DNA damage caused by etheno adducts.
• Structural Biology: A tool for probing nucleic acid structure and conformation when etheno-modified bases are incorporated.
• Enzyme Kinetics: Serves as a modified substrate in kinetic assays to determine enzyme inhibition constants and catalytic efficiency.
• Diagnostic Assay Development: Potential use in developing sensitive assays for detecting specific DNA lesions or enzyme activities.

Basic Information

Product Name	3,N4-Ethenocytidine 5'-Triphosphate*Sodium
CAS No.	103226-14-8
Molecular Formula	C12H15N3O14P3Na (or similar, based on sodium salt form)
Molecular Weight	Contact for details
Synonyms	1,N6-Ethenocytidine-5'-triphosphate sodium salt; εdCTP Na; 3,N4-ε-Cytidine triphosphate sodium; Etheno-dCTP; 1,N6-Etheno-2'-deoxycytidine-5'-triphosphate sodium; Modified nucleotide triphosphate; DNA adduct precursor; Cytidine etheno adduct triphosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized to confirm identity and purity. Certificates of Analysis (COA) detailing purity, HPLC analysis, and other relevant parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a non-frost-free freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5%
Biological Activity	Tested as substrate/inhibitor for specific enzymes

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.