Description

1,N6-Etheno-2'-Deoxy-Adenosine 5'-Monophosphate Sodium Salt is a modified nucleotide analog, specifically an etheno derivative of 2'-deoxyadenosine monophosphate. This compound is a valuable biochemical tool and research standard, primarily used to study DNA damage, mutagenesis, and the mechanisms of DNA repair enzymes. It serves as a critical reference material for analytical laboratories and research institutions focused on nucleic acid chemistry and toxicology. The product is supplied as a high-purity sodium salt to ensure stability and solubility for experimental applications.

Application

• Biochemical Research: Used as a standard and substrate in studies of DNA adduct formation, repair pathways, and mutagenic events.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for the quantification of etheno-DNA adducts in biological samples via HPLC-MS or immunoassays.
• Enzymology Studies: Employed to investigate the activity and specificity of DNA repair enzymes, such as alkylpurine-DNA-N-glycosylases.
• Toxicology and Biomarker Research: Acts as a biomarker for exposure to certain carcinogens, like vinyl chloride, that induce etheno adducts in DNA.
• Pharmaceutical Development: Utilized in early-stage research for understanding drug-induced DNA damage and developing protective agents.

Basic Information

Item	Detail
Product Name	1,N6-Etheno-2'-Deoxy-Adenosine 5'-Monophosphate Sodium Salt
CAS No.	103213-55-4
Molecular Formula	C12H14N5O6P • xNa
Molecular Weight	Contact for details
Synonyms	1,N6-Etheno-2'-deoxyadenosine 5'-monophosphate sodium salt; εdA 5'-Monophosphate sodium salt; 1,N6-Etheno-dAMP Na salt; Etheno-deoxyadenosine monophosphate sodium salt; 1,N6-Etheno-2'-deoxyadenosine-5'-monophosphoric acid sodium salt; ε-dA-5'-MP sodium salt; DNA Adduct Standard (1,N6-etheno-dA)
EINECS	Contact for details

Quality Control

Our 1,N6-Etheno-2'-Deoxy-Adenosine 5'-Monophosphate Sodium Salt is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or moisture should be avoided to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.