Description

Gtp Tris Salt is a high-purity biochemical reagent widely used in molecular biology and pharmaceutical research. This compound serves as a critical substrate and energy source for enzymatic reactions, particularly in nucleic acid synthesis and metabolic studies. It is essential for researchers and manufacturers in the biotechnology, diagnostic, and pharmaceutical industries requiring reliable and consistent raw materials for sensitive applications.

Application

• Enzymatic Synthesis: As a substrate for RNA polymerases and other nucleotide-dependent enzymes in in vitro transcription and nucleic acid amplification.
• Metabolic Research: Used in studies of cellular energy metabolism, signal transduction pathways, and GTP-binding proteins (G-proteins).
• Diagnostic Kit Manufacturing: A key component in the formulation of master mixes for PCR, RT-PCR, and other molecular diagnostic assays.
• Pharmaceutical Development: Employed in research and development for drugs targeting nucleotide metabolism and related pathways.
• Biochemical Assays: Utilized in high-throughput screening (HTS) and enzyme activity assays that require GTP as a cofactor or substrate.
• Cell Culture & Microbiology: Applied in specialized cell culture media and studies of bacterial or viral replication mechanisms.

Basic Information

Product Name	Gtp Tris Salt
CAS No.	103192-46-7
Molecular Formula	C10H16N5O14P3 • C4H11NO3
Molecular Weight	Approx. 623.31 g/mol (Free acid) + 121.14 g/mol (Tris)
Synonyms	Guanosine-5'-triphosphate tris salt; GTP Tris Salt; 5'-GTP Tris Salt; Guanosine 5'-(tetrahydrogen triphosphate) tris(2-amino-2-hydroxymethyl-propane-1,3-diol) salt; Tris(hydroxymethyl)aminomethane guanosine 5'-triphosphate salt; GTP-Tris; Tris GTP; GTP, Tris salt
EINECS	Contact for details

Quality Control

Our Gtp Tris Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Anhydrous basis)
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	7.0 - 8.5
Endotoxin (LAL)	< 10 EU/mg (for applicable grades)
Filter Sterility	Passes test (for sterile-filtered grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.