Description

Gonadotropin-Releasing Hormone (1-6) Trifluoroacetate Salt is a high-purity synthetic peptide fragment of the gonadotropin-releasing hormone (GnRH), a key neurohormone in the endocrine system. This compound is essential for research and development in neuroendocrinology and reproductive biology, serving as a critical reference standard and a precursor for further peptide synthesis. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on hormone-related therapeutics and diagnostic assays.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in drug development and quality control.
• Biochemical Research: A vital tool for studying the structure-activity relationship (SAR) of GnRH and its interaction with receptors.
• Peptide Synthesis Intermediate: Serves as a key building block for the synthesis of longer, modified GnRH analogs and conjugates.
• Endocrine & Reproductive Studies: Applied in *in vitro* and *in vivo* research models to investigate pituitary-gonadal axis function and regulation.
• Diagnostic Development: Used in the development and manufacturing of immunoassays and diagnostic kits for hormonal disorders.

Basic Information

Product Name	Gonadotropin-Releasing Hormone (1-6) Trifluoroacetate Salt
CAS No.	103067-73-8
Molecular Formula	C38H54N12O10 • xC2HF3O2
Molecular Weight	862.92 g/mol (Free base, C38H54N12O10)
Synonyms	GnRH (1-6) TFA Salt; Gonadorelin (1-6) Fragment TFA Salt; Luteinizing Hormone-Releasing Hormone (1-6) TFA Salt; LH-RH (1-6) TFA Salt; Pyro-Glu-His-Trp-Ser-Tyr-Gly TFA Salt; pGlu-His-Trp-Ser-Tyr-Gly TFA Salt; Gonadoliberin (1-6) TFA Salt
EINECS	Contact for details

Quality Control

Our Gonadotropin-Releasing Hormone (1-6) Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.