Description

Ethenesulfonyl Fluoride, 1-Bromo- CAS NO 103020-98-0 is a high-value, reactive organosulfur building block featuring both a sulfonyl fluoride (SuFEx click chemistry handle) and a bromo substituent. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel drug candidates, covalent inhibitors, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing covalent protease inhibitors and other targeted therapeutics utilizing SuFEx chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Enables the creation of activity-based probes (ABPs) for studying enzyme function and target engagement.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for developing functional polymers with unique surface properties.
• Peptide & Protein Modification: Facilitates site-specific labeling and conjugation of biomolecules.
• Library Synthesis for Drug Discovery: A versatile reagent for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	Ethenesulfonyl Fluoride, 1-Bromo-
CAS No.	103020-98-0
Molecular Formula	C2H2BrFO2S
Molecular Weight	189.00 g/mol
Synonyms	1-Bromoethenesulfonyl Fluoride; 1-Bromoethylene-1-sulfonyl Fluoride; (1-Bromoethene-1-sulfonyl)fluoride; Bromoethenesulfonyl Fluoride; Vinylsulfonyl Fluoride, 1-Bromo-; 1-Bromo-1-fluoro sulfonyl ethene; 1-Bromo-1-fluorosulfonyl ethylene; 1-Bromoethene-1-sulfonyl fluoride
EINECS	Contact for details

Quality Control

We supply Ethenesulfonyl Fluoride, 1-Bromo- in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.