Description

Neuropeptide Y (2-36) (Porcine) is a specific, truncated fragment of the full-length Neuropeptide Y (NPY) hormone, corresponding to amino acid residues 2 through 36. This bioactive peptide is a critical research tool for investigating the structure-activity relationships and signaling pathways of NPY, a key regulator of numerous physiological processes including appetite, anxiety, and cardiovascular function. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neuroscience, metabolic disorders, and drug discovery.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of NPY receptor subtypes (Y1, Y2, Y4, Y5, Y6), neuronal signaling, and synaptic transmission.
• Pharmacological Studies: Essential for in vitro and in vivo assays to screen and characterize novel NPY receptor agonists or antagonists for therapeutic development.
• Metabolic Disorder Research: Applied in models investigating NPY's role in energy homeostasis, food intake regulation, and obesity.
• Cardiovascular Research: Utilized to study NPY's effects on blood pressure, heart rate, and vascular tone.
• Biochemical Standard: Serves as a high-purity calibrant in analytical methods such as HPLC and mass spectrometry for peptide quantification.
• Antibody Production & Immunoassays: Acts as an immunogen for generating specific antibodies or as a standard in ELISA and RIA development.

Basic Information

Product Name	Neuropeptide Y (2-36) (Porcine)
CAS No.	102961-52-4
Molecular Formula	C185H285N55O57S
Molecular Weight	4181.7 g/mol
Synonyms	NPY (2-36), Porcine; Neuropeptide Y (porcine) fragment 2-36; NPY (2-36), pig; Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 (porcine); H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
EINECS	Contact for details

Quality Control

Our Neuropeptide Y (2-36) (Porcine) is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to guarantee the material meets the high standards required for pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by ESI-MS or MALDI-TOF
Purity (HPLC)	≥ 95% (Area percent at 214 nm or 280 nm)
Peptide Content	≥ 80% (by AAA or quantitative NMR)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.