Description

(2S)-2-(2-Oxopyrrolidin-1-Yl)Butanoic Acid CAS NO 102849-49-0 is a high-purity chiral intermediate featuring a butanoic acid moiety linked to a 2-pyrrolidinone ring. This compound is valued for its role as a key building block in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and metabolic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and production of novel drug candidates, especially for central nervous system (CNS) and metabolic disorder treatments.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in multi-step synthetic routes for constructing complex API structures.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and protease inhibitors due to its pyrrolidinone scaffold.
• Asymmetric Synthesis: Employed as a starting material or intermediate in asymmetric catalytic processes to introduce stereochemical complexity.
• Bioconjugation & Prodrug Development: The carboxylic acid group enables conjugation chemistry for creating prodrugs or bioconjugates with improved pharmacokinetic properties.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(2S)-2-(2-Oxopyrrolidin-1-Yl)Butanoic Acid
CAS No.	102849-49-0
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(S)-2-(2-Oxopyrrolidin-1-yl)butanoic acid; (2S)-2-(2-Oxo-1-pyrrolidinyl)butanoic Acid; L-2-(2-Oxopyrrolidino)butyric Acid; 1-Pyrrolidineacetic acid, α-ethyl-2-oxo-, (αS)-; (S)-α-Ethyl-2-oxo-1-pyrrolidineacetic acid; UNII-3J1WJ3Y6K9; 3J1WJ3Y6K9; (S)-2-(2-Oxopyrrolidin-1-yl)butyric acid
EINECS	Contact for details

Quality Control

Our (2S)-2-(2-Oxopyrrolidin-1-Yl)Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.