Description

Coenzyme A Trilithium Salt Dihydrate is a high-purity, stabilized lithium salt form of the essential metabolic cofactor, Coenzyme A. This compound is critical for facilitating acyl group transfer reactions in key biochemical pathways, including fatty acid metabolism and the citric acid cycle. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies for enzymatic assays, biochemical research, and as a reference standard.

Application

• Biochemical Research & Enzyme Assays: Essential cofactor for in vitro studies of acyltransferase, synthetase, and other CoA-dependent enzymes.
• Diagnostic Reagent Manufacturing: Key component in clinical diagnostic kits for measuring metabolic enzyme activities (e.g., for liver function).
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and method development in drug discovery and life sciences.
• Metabolic Pathway Analysis: Substrate for studying fatty acid synthesis, oxidation, and the Krebs cycle in cellular and molecular biology.
• Cell Culture & Biotechnology: Supplement in specialized cell culture media to support metabolic functions in certain cell lines.

Basic Information

Product Name	Coenzyme A Trilithium Salt Dihydrate
CAS No.	102778-59-6
Molecular Formula	C21H36Li3N7O16P3S • 2H2O
Molecular Weight	821.41 g/mol (anhydrous basis)
Synonyms	CoA Trilithium Salt; Coenzyme A Li Salt; CoA-Li; 3'-Phosphoadenosine 5'-diphospho-pantetheine trilithium salt; CoASH Lithium Salt; CoA (Lithium); Adenosine 3'-phosphate 5'-diphosphate, pantetheine derivative, trilithium salt
EINECS	Contact for details

Quality Control

Our Coenzyme A Trilithium Salt Dihydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	4.0% - 8.0%
pH (1% Solution)	5.0 - 7.0
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.