Description

Biocytin Hydrazide Hydrochloride is a high-purity, chemically modified derivative of biotin designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers who require a reliable, site-specific reagent for attaching biotin tags to biomolecules, enabling sensitive detection and purification. It is primarily utilized in the life sciences sector for developing diagnostic assays, targeted drug delivery systems, and advanced proteomics research tools.

Application

• Bioconjugation Reagent: For the site-specific labeling of antibodies, proteins, peptides, and oligonucleotides with biotin tags.
• Diagnostic Assay Development: A key component in the manufacture of ELISA kits, lateral flow assays, and other immunoassays that utilize streptavidin-biotin technology.
• Affinity Purification Probes: Used to create immobilized ligands for the capture and purification of target molecules via streptavidin or avidin matrices.
• Cell Surface Labeling: Enables the tagging of cell surface receptors and carbohydrates for flow cytometry and microscopy studies.
• Drug Delivery & Targeting: Facilitates the development of biotinylated drug conjugates and nanoparticles for targeted therapeutic applications.
• Proteomics & Biomarker Discovery: Employed in pull-down assays and mass spectrometry workflows to isolate and identify protein complexes.

Basic Information

Product Name	Biocytin Hydrazide Hydrochloride
CAS No.	102743-85-1
Molecular Formula	C16H29N5O3S • HCl
Molecular Weight	424.0 g/mol (Hydrochloride salt)
Synonyms	Nε-Biotinyl-L-lysine Hydrazide Hydrochloride; Biocytin Hydrazide HCl; Biotin-L-lysine Hydrazide Hydrochloride; (+)-Biotinyl-L-lysine Hydrazide Hydrochloride; Biotin Amide of L-Lysine Hydrazide Hydrochloride; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N6-(hydrazinecarbonyl)-L-lysine Hydrochloride
EINECS	Contact for details

Quality Control

Our Biocytin Hydrazide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.